The GlycoChemBio Group of the Department of Organic Chemistry at the University of Granada has published in the Chapter 6 of Volume 3 of the series entitled “Carbohydrate Chemistry. Proven Synthetic Methods” (CRC Editorial) a reliable and efficient method for the preparation of glycosyl vinyl sulfones, compounds of high versatility for the bioconjugation and immobilization of sugars to other biomolecules and solid surfaces, respectively.